1 You just download cheat engine,
2 boot up the game you want to cheat in,
3 shrink the game while it's still running Tab + alt or ctrl + alt + delete
4 launch cheat engine,
5 click on the mini computer icon on the left corner
6 select the game you want to cheat in.
You are going to be searching for value!
For example, say you have 63 gold. Shrink the game down and pull up your cheat engine. Type in 63, and you should already be on exact value, hit First scan. A long list of number will come up. Now go back to the game and buy something.
For example, you spent 20 gold so you only have 43 gold. You could either search for 43 on exact value and hit next scan, or you decreased by and type in 20 and look for the value on the left side.
If you see only one selection with 43 come up your golden. Double click on 43 and then you should see a the entire line of code is now in the bottom tab. Double click on 43 and a little bar will appear in the center of cheat engine. Choose the value you want, in Bioshock you can't have more then 500 gold.
So type in 500, go back to the game, go to the store and you should now have 500 gold. Con if click on box under active in cheat engine it will freeze the value so it can never go down.
Keep in mind if you do this in a multi player game you will be banned from the game. It's recommend that if you want to dare using cheat engine in single player mod that you go off line so the servers can't detect your cheating. And even then there is a risk that if you go back online especially for multi player that they maker of the game will catch you and ban you for life.
Most people just use cheat engine for unlimited money so you don't have to farm for it.